Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC DDP-38003 dihydrochloride | 1831167-98-6 | 99.3% | 423.38 | 100 MG
Supplier: Medchemexpress LLC HY19612A100MG
DDP-38003 dihydrochloride is a novel, orally available inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) with an IC50 of 84 nM. It exhibits in vivo efficacy after oral administration, determining a 62% increased survival in mouse leukemia models with evidence of KDM1A inhibition. The half-life of DDP-38003 is 8 hours. A significant dose-dependent increase of mice survival is obtained by DDP-38003 treatment. DDP-38003 is a potential oral anticancer agent.
- Novel, orally available inhibitor of KDM1A/LSD1
- IC50 of 84 nM against KDM1A
- More active in reducing colony forming ability and inducing differentiation of THP-1 cells compared to the 1R, 2S analogue
- Exhibits in vivo efficacy after oral administration
- Determines 62% increased survival in mouse leukemia models
- Half-life of 8 hours
- Potential oral anticancer agent
- Appearance: Solid, brown to reddish brown
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?