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ABclonal Technology DDR1/MCK10/CD167a Rabbit mAb
Supplier: ABclonal Technology A2270520UL
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment These kinases are involved in the regulation of cell growth differentiation and metabolism The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain and that are activated by various types of collagen Expression of this protein is restricted to epithelial cells particularly in the kidney lung gastrointestinal tract and brain In addition it has been shown to be significantly overexpressed in several human tumors Alternatively spliced transcript variants encoding different isoforms have been described for this gene
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