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Cayman Chemical Decamethonium (bromide), Purity: ≥98%, CAS: 541-22-0, 10 g
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Catalog No. 503015873
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A depolarizing neuromuscular blocking agent; a partial agonist of muscle-type nAChRs; activates α1β1-containing adult mouse muscle-type nAChRs expressed in X. laevis oocytes (EC50 = 40 µM); a nondepolarizing antagonist of neuronal-type nAChRs, inhibiting mouse α7-, α3β2-, α3β4-, and α4β2-containing receptors (IC50s = 7.4, 405, 28, and 59 µM, respectively); a competitive antagonist of α4β2-containing nAChRs expressed in SH-EP1 cells (IC50 = 52 µM for the human receptor); inhibits electric eel AChE; blocks electrically-evoked tibialis muscle twitches in anesthetized cats with ED95 values of 35 and 70 µg/kg for cats under chloralose and ether anesthesia, respectively

Catalog No. 50-301-5873 Supplier Cayman Chemical Supplier No. 2490710 G
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A depolarizing neuromuscular blocking agent; a partial agonist of muscle-type nAChRs; activates α1β1-containing adult mouse muscle-type nAChRs expressed in X. laevis oocytes (EC50 = 40 µM); a nondepolarizing antagonist of neuronal-type nAChRs, inhibiting mouse α7-, α3β2-, α3β4-, and α4β2-containing receptors (IC50s = 7.4, 405, 28, and 59 µM, respectively); a competitive antagonist of α4β2-containing nAChRs expressed in SH-EP1 cells (IC50 = 52 µM for the human receptor); inhibits electric eel AChE; blocks electrically-evoked tibialis muscle twitches in anesthetized cats with ED95 values of 35 and 70 µg/kg for cats under chloralose and ether anesthesia, respectively

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