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Apexbio Technology LLC Decanoyl-RVKR-CMK(Synonyms: Dec-RVKR-CMK, Decanoyl-Arg-Val-Lys-Arg-chloromethylketone), 500ug, CAS: 150113-99-8.
Supplier: Apexbio Technology LLC B54370.5
Decanoyl-RVKR-CMK (CAS 150113-99-8) is a small molecule inhibitor targeting proprotein convertases (PCs) enzymes responsible for processing precursor proteins into biologically active peptides and activating various enzymes and growth factors This inhibitor has been observed to suppress regulated secretion and maturation of the neuroendocrine peptide VGF in PC12 cells Additionally topical administration inhibited epidermal proliferation induced by phorbol ester treatment in K5-PACE4 transgenic mice and reduced basal keratinocyte proliferation Decanoyl-RVKR-CMK is relevant in studies investigating PCs as potential targets for therapeutic approaches in cancer and related proliferative disorders
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