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Cayman Chemical DehydroabIetIc AcId 500mg
Supplier: Cayman Chemical 33722500 MG
A diterpene acid with diverse biological activities; active against L. amazonensis promastigotes (IC50 = 40 UG/ml); increases the number of mitochondrial ridges, decreases mitochondrial outer membrane rupture, and increases the expression of FSP1 and COQ10 in an HL7720 cell model of oleic acid-induced ferroptosis at 2.5, 5, and 10 µM; reduces hepatic total cholesterol and triglyceride levels, ferroptosis, and lipid peroxidation in a mouse model of high-fat diet-induced NAFLD at 10 and 20 mg/kg; found in wood industry effluents and is considered a pollutant; increases oxygen consumption and cellular heat production and reduces cellular ATP content in isolated rainbow trout hepatocytes
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