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Cayman Chemical DehydroascorbIc AcId 500mg
Supplier: Cayman Chemical 29089500 MG
An oxidized form of ascorbic acid; inhibits hydrogen peroxide-induced cell death in murine astrocytes by approximately 74 and 83% at 0.5 and 1 mM, respectively; increases GPX and glutathione reductase activity and inhibits ROS production in hydrogen peroxide-treated astrocytes at 1 mM; increases cerebral blood flow and reduces infarct volume and mortality in a mouse model of cerebral ischemia-reperfusion injury induced by transient MCAO when administered prior to ischemia at 40 and 250 mg/kg; reduces infarct volume in a permanent MCAO mouse model when administered pre- or post-ischemia at 250 and 500 mg/kg, respectively
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