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Medchemexpress LLC Dehydroepiandrosterone sulfate (sodium) | 1099-87-2 | >98.0% | 100 MG
Supplier: Medchemexpress LLC HYB0765100MG
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. It exhibits non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. This compound can partially penetrate the blood-brain barrier, making it suitable for neurological research.
- Inhibits GABAA receptor-mediated chloride influx
- Enhances NMDA receptor activity through σ1 receptors
- Exerts anti-inflammatory, anti-glucocorticoid and antidepressant effects
- Increases convulsive sensitivity
- Participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation
- Used in the study of depression, post-traumatic stress disorder (PTSD), and Alzheimer's disease
- May be a biomarker for cardiovascular disease mortality
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