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Cayman Chemical DehydroevodIamInhydrochLR 50mg
SDP

Supplier:  Cayman Chemical 2510150 MG

Encompass_Preferred

An inhibitor of USP7 (IC50 424 nM) dose-dependently inhibits USP7-mediated p53 deubiquitination in a cell-free assay (IC50 ~0.8 UM) and in vitro selective for USP7 over a panel of proteases including aspartic serine and metalloproteases (IC50s 10 UM) several cysteine proteases (IC50s 1 and 10 UM) and the deubiquitinating enzymes UCH-L1 (IC50 1 UM) and SENP1 (IC50 10 UM increases p53 levels inhibits proliferation of HCT116 cells (IC50 ~1 UM) induces apoptosis in HCT116 cells

Catalog No. 50-293-2644


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