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Cayman Chemical DelgocItInIb 10mg

Supplier: Cayman Chemical 3830710 MG
An inhibitor of JAK1, JAK2, JAK3, and TYK2 (IC50s = 2.8, 2.6, 13, and 58 nM, respectively); is selective for JAK1, JAK2, JAK3, and TYK2 over LCK (IC50 = 5,800 nM); inhibits IL-31-induced increases in STAT3 phosphorylation levels in A549 cells (IC50 = 25 nM); reduces IL-31-induced scratching in mice in a dose-dependent manner
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