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Cayman Chemical DeltarasInhydrochlorIde 10mg
SDP

Catalog No. 502892644
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A small molecule that binds to the farnesyl-binding pocket of PDEδ (Kd = 41 nM) in cells thus inhibiting its interaction with KRAS and disrupting RAS signaling; reduces proliferation and increases cell death of Panc-Tu-I tumor cells at 5 μM in a human pancreatic ductal adenocarcinoma cell model; reduces tumor growth at a dose of 10 mg/kg in nude mice xenografted with pancreatic carcinoma

Catalog No. 50-289-2644 Supplier Cayman Chemical Supplier No. 900153610 MG
May include imposed supplier surcharges.
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A small molecule that binds to the farnesyl-binding pocket of PDEδ (Kd = 41 nM) in cells thus inhibiting its interaction with KRAS and disrupting RAS signaling; reduces proliferation and increases cell death of Panc-Tu-I tumor cells at 5 μM in a human pancreatic ductal adenocarcinoma cell model; reduces tumor growth at a dose of 10 mg/kg in nude mice xenografted with pancreatic carcinoma

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