Demeclocycline hydrochloride, Thermo Scientific Chemicals

Description

Demeclocycline hydrochloride is used as an antibiotic related to tetracycline and produced by streptomyces aureofaciens, and used to maintain effective blood levels for longer periods of time, used as a fluorescent bone-labeling agent in bone histomorphometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Demeclocycline hydrochloride is used as an antibiotic related to tetracycline and produced by streptomyces aureofaciens, and used to maintain effective blood levels for longer periods of time, used as a fluorescent bone-labeling agent in bone histomorphometry.

Solubility
Soluble in water.

Notes
Keep container tightly closed. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 64-73-3
• Molecular Formula: C21H22Cl2N2O8
• Molecular Weight (g/mol): 501.313
• MDL Number: MFCD00082371
• InChI Key: OAPVUSSHCBRCOL-KBHRXELFSA-N
• Synonym: demeclocycline hydrochloride, demeclocycline hcl, declomycin, detravis, ledermycine, clortetrin, ledermycin, ledermicina, veraciclina, demeplus
• PubChem CID: 54686764
• IUPAC Name: (4S,4aS,5aS,6S,12aR)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride
• SMILES: CN(C)C1C2CC3C(C4=C(C=CC(=C4C(=C3C(=O)C2(C(=C(C1=O)C(=O)N)O)O)O)O)Cl)O.Cl

• Melting Point: >245°C (decomposition)
• Color: Yellow
• Quantity: 250 mg
• Beilstein: 3849198
• Merck Index: 14,2886
• Solubility Information: Soluble in water.
• Formula Weight: 501.32
• Physical Form: Powder
• Chemical Name or Material: Demeclocycline hydrochloride

Safety and Handling

Hazard Category	Warning
Hazard Statement	GHS H Statement H317 May cause an allergic skin reaction.
Precautionary Statement	GHS P Statement P261-P280-P363-P321-P333+P313-P501a Avoid breathing dust/fume/gas/mist/vapors/spray. Wear protective gloves/protective clothing/eye protection/face protection. Wash contaminated clothing before reuse. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. Dispose of contents/container in accordance with local/regional/national/international regulations.
EINECSNumber	200-592-2
RTECSNumber	QI7700000
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only