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Sigma Aldrich Fine Chemicals Biosciences Denaturation Solution for

Supplier:  Sigma Aldrich Fine Chemicals Biosciences N15314L

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Sigmas denaturing SOLUTIONon is a strong base that denatures double-stranded DNA so that it can be efficiently transferred to nylon membrane and subsequently hybridized to labeled probe. When used with a depurination SOLUTIONon treatment results in the hydrolysis of the phosphodiester backbone at the sites of depurination allowing for more efficient transfer of large DNA in neutral Southern transfers.

Catalog No. 50-290-0858


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