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Medchemexpress LLC Dendrotoxin-I TFA | 99.9% | 7149.24 | 500 UG
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Supplier:  Medchemexpress LLC HYP3055A500UG

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Dendrotoxin-I TFA is a potent K+ channel blocker effective against voltage-gated potassium channel subunits KV1.1, KV1.2, and KV1.6, with IC50s ranging from 0.13-50 nM. This neurotoxin holds potential in cancer research, as demonstrated by its significant tumor growth inhibition effect when combined with hyperthermia in nude mice with MCF-7 cells.

  • Potent K+ channel blocker
  • Effective against voltage-gated potassium channel subunits KV1.1, KV1.2, and KV1.6
  • Exhibits neurotoxic properties
  • Potential for use in cancer research
  • Demonstrated tumor growth inhibition in in vivo studies

Catalog No. 50-004-00125


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