Deoxy-bigCHAP, Thermo Scientific Chemicals

Description

Analog of CHAPS and CHAPSO

Deoxy-bigCHAP is used for membrane solubilization. It is easily removed by dialysis and its absorption at UV region is very low. N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide is used for membrane solubilization and proteomic analysis. N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide (deoxy-BigCHAP) is a non-ionic detergent that solubilizes cell membrane.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Deoxy-bigCHAP is used for membrane solubilization. It is easily removed by dialysis and its absorption at UV region is very low. N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide is used for membrane solubilization and proteomic analysis. N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide (deoxy-BigCHAP) is a non-ionic detergent that solubilizes cell membrane.

Solubility
Soluble in water at 50mg/ml. Also soluble in DMSO or methanol.

Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 86303-23-3
• Molecular Formula: C42H75N3O15
• Molecular Weight (g/mol): 862.068
• MDL Number: MFCD00161482
• InChI Key: OJSUWTDDXLCUFR-HGZMBBKESA-N
• Synonym: N,N-Bis[3-(D-gluconamido)propyl]deoxycholamide
• PubChem CID: 446320
• IUPAC Name: (2R,3S,4R,5R)-N-[3-[[(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]-[3-[[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino]propyl]amino
• SMILES: CC(CCC(=O)N(CCCNC(=O)C(C(C(C(CO)O)O)O)O)CCCNC(=O)C(C(C(C(CO)O)O)O)O)C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C

• Color: White
• Physical Form: Powder
• Quantity: 250 mg
• Merck Index: 14,1214
• Solubility Information: Soluble in water at 50mg/ml; Also soluble in DMSO or methanol.
• Formula Weight: 862.05
• Chemical Name or Material: Deoxy-bigCHAP

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only