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Medchemexpress LLC Deoxycholic acid | 83-44-3 | 392.57 | 500 MG
Supplier: Medchemexpress LLC HYN0593500MG
Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism that activates the G protein-coupled bile acid receptor TGR5. It is for research use only and not sold to patients.
- Activates the G protein-coupled bile acid receptor TGR5.
- Functions as a microbial metabolite.
- Functions as a human endogenous metabolite.
- In vitro, it induces production of gastric cancer cell line MGC803 resistant to acidified bile acids, enhancing survival and proliferation activity under bile acid stress.
- DCA-induced resistant cells show altered morphology, elevated telomerase activity, improved cell viability, and reduced apoptosis compared to normal MGC803 cells.
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