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Cayman Chemical DeoxypodophylotoxIn 100mg

Supplier: Cayman Chemical 36434100 MG
A flavolignan with diverse biological activities; inhibits tubulin polymerization in a cell-free assay at 50 nM; inhibits COX-2 and 5-LO in isolated mouse bone marrow-derived mast cells stimulated with KL, IL-10, and LPS (IC50s = 1.89 and 0.37 µM, respectively); reduces viral yield in the supernatant of HSV-1- or HSV-2-infected MRC-5 cells at 0.02 UG/ml; inhibits aggregation of rabbit platelets induced by PAF, collagen, or arachidonic acid; induces mortality in P. rapae fifth instar larvae (LC50 = 0.02 g/L); reduces tumor growth in a CT26 murine colon cancer model at 70 UG/kg
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