Desmosine, MP Biomedicals™

Description

Responsible for the cross-linking of elastin, leading to the formation of insoluble fibers. Desmosine, MP Biomedicals is a tetrafunctional, pyridinium ring-containing amino acids involved in elastin cross-linking. Urinary excretion of desmosine is an indi

A desmosine cross-link is formed from three allysyl side chains plus one unaltered lysyl side chain from the same or neighbouring polypeptides. Desmosine is responsible for the cross-linking of elastin. Urinary excretion of desmosine is a useful indicator of elastin breakdown resulting from increased elastase activity. It also acts as a biomarker of elastin degradation in chronic obstructive pulmonary disease.

Specifications

Chemical Identifiers

• CAS: 11003-57-9
• Molecular Formula: C24H40N5O8+
• Molecular Weight (g/mol): 526.611
• InChI Key: VEVRNHHLCPGNDU-MUGJNUQGSA-O
• Synonym: unii-4mol2j0tly, desmosine, 4mol2j0tly, +-desmosine, 4-4s-4-amino-4-carboxybutyl-1-5s-5-amino-5-carboxypentyl-3,5-bis 3s-3-amino-3-carboxypropyl pyridinium, pyridinium, 4-4-amino-4-carboxybutyl-1-5-amino-5-carboxypentyl-3,5-bis 3-amino-3-carboxypropyl, pyridinium, 4-4-amino-4-carboxybutyl-1-5-amino-5-carboxypentyl-3,5-bis 3-amino-3-carboxypropyl-van
• PubChem CID: 15942890
• ChEBI: CHEBI:37628
• IUPAC Name: (2S)-2-amino-6-[4-[(4S)-4-amino-4-carboxybutyl]-3,5-bis[(3S)-3-amino-3-carboxypropyl]pyridin-1-ium-1-yl]hexanoic acid
• SMILES: C1=C(C(=C(C=[N+]1CCCCC(C(=O)O)N)CCC(C(=O)O)N)CCCC(C(=O)O)N)CCC(C(=O)O)N

• Quantity: 5 mg
• Formula Weight: 526 (anhydrous)
• Percent Purity: 99%
• Physical Form: Solid

Safety and Handling

Recommended Storage

4°C, desiccate

WARNING: Reproductive Harm - www.P65Warnings.ca.gov