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Medchemexpress LLC Destruxin B | 2503-26-6 | 1 MG
SDP

Supplier:  Medchemexpress LLC HYN66901MG

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Destruxin B is a cyclodepsipeptide isolated from the entomopathogenic fungus Metarhizium anisopliae. It exhibits both insecticidal and anticancer activities. This compound induces apoptosis via a Bcl-2 Family-dependent mitochondrial pathway in human non-small cell lung cancer cells, significantly activating caspase-3 and reducing tumor cell proliferation.

  • Induces apoptosis through a Bcl-2 Family-dependent mitochondrial pathway
  • Activates caspase-3 in human non-small cell lung cancer cells
  • Reduces tumor cell proliferation both in vitro and in vivo
  • Inhibits cell proliferation in H1299 and A549 cells
  • Attenuates tumor growth in animal models

Catalog No. 50-004-20020


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