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Medchemexpress LLC Dexamethasone phosphate disodium | 2392-39-4 | 99.94% | 516.40 | 500 MG
SDP

Supplier:  Medchemexpress LLC 500MGHYB1829A

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Dexamethasone phosphate disodium is an orally active Glucocorticoid receptor agonist. It regulates various transcription factors, including activator protein-1, nuclear factor-AT, and nuclear factor-kB, to influence inflammatory response genes.

  • Potently inhibits granulocyte-macrophage colony stimulating factor (GM-CSF) release from A549 cells
  • Induces transcription of the β2-receptor
  • Inhibits 3xκB (NF-κB, IκBα, and I-κBβ) activity
  • Efficiently inhibits lipopolysaccharide (LPS)-induced inflammation in vivo
  • Decreases recruitment of granulocytes and spontaneous production of oxygen radicals in vivo

Catalog No. 50-003-65906


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