Dextran Sulfate Sodium Salt, Colitis Grade (36,000 to 50,000), MP Biomedicals™

Catalog No.	Quantity
MP216011001	1 g
ICN16011010	10 g
MP216011025	25 g
ICN16011050	50 g
ICN16011080	100 g
ICN16011090	500 g
02-160-11091	1000 g

Catalog No. MP216011001 Supplier MP Biomedicals, Inc Supplier No. 0216011001

Description

Induces severe colitis (inflammatory bowel disease) in laboratory animals

Dextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to trigger colitis in mice and rats when administered in drinking water. DSS binds to medium-chain-length fatty acids in the colon and induces intestinal inflammation. Colitis-grade DSS (MW = 36,000 to 50,000) from MP Bio is one of the most widely used products based on peer reviewed scientific publications.

• Induces severe colitis (inflammatory bowel disease)
• Highest sulfur content – 19%
• Highest chirality - +104° of specific rotation
• Lowest pH – 6.2 at 1% solution

Specifications

• Color: White
• pH: 5 to 7.11 (1% aqueous solution)
• Physical Form: Powder
• CAS: 9011-18-1
• Boiling Point: 310°C
• Melting Point: 92°C
• Molecular Formula: (C6H7O5)m(C6H7O5)n
• MDL Number: MFCD00081551
• Solubility Information: Soluble in water
• Quantity: 1 g
• InChI Key: BLFLLBZGZJTVJG-UHFFFAOYSA-N
• SMILES: *-OC[C@H]1O[C@H](OC[C@H]2O[C@H](-*)[C@H](O[*])[C@@H](O[*])[C@@H]2O[*])[C@H](O[*])[C@@H](O-*)[C@@H]1O[*]
• IUPAC Name: Dextran sulfate sodium salt
• Molecular Weight (g/mol): 40,000
• Grade: Colitis Grade
• For Use With (Application): Used for inducing ulcerative colitis in animals and extensively to study colon cancer developing in relation to colonic inflammation
• Moisture: <10%
• Packaging: Plastic Container

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.