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Apexbio Technology LLC Dextromethorphan hydrobromide 125-69-9 5g
Supplier: Apexbio Technology LLC B34785000
Dextromethorphan hydrobromide is a small-molecule inhibitor targeting neuronal ion channels including voltage-gated Na and Ca channels and antagonizing N-methyl-D-aspartate (NMDA) receptors It is designed to inhibit voltage-gated inward currents and NMDA receptor-induced currents thereby modulating neuronal excitability and neuroprotection pathways Dextromethorphan hydrobromide exerts its biological activity primarily through inhibition of voltage-gated Na and Ca channels and antagonism of NMDA receptors In cultured cortical neurons dextromethorphan hydrobromide demonstrates inhibition of NMDA receptor-induced currents with an IC value of approximately 80 M Based on these pharmacological properties dextromethorphan hydrobromide holds research potential in the investigation of excitotoxicity neuronal injury mechanisms and therapeutic strategies for ischemic or neurodegenerative conditions
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