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Apexbio Technology LLC DGAT-1 inhibitor 701232-20-4 200mg
Supplier: Apexbio Technology LLC A3363200
DGAT-1 inhibitor (CAS 701232-20-4) also known as T863 is an orally active small molecule that selectively inhibits diacylglycerol acyltransferase 1 (DGAT1) DGAT1 is responsible for catalyzing the final step in triglyceride biosynthesis T863 suppresses enzyme activity by specifically binding to the acyl-CoA binding site of DGAT1 exhibiting an IC50 of 15 nM without affecting enzymatic activities of human DGAT2 MGAT2 or MGAT3 This compound serves as a research tool for investigating DGAT1-mediated lipid synthesis and exploring lipid metabolic disorders using cellular and animal models
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