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Cayman Chemical DGlucosamIn6phosphAThy 50mg

Supplier: Cayman Chemical 3086950 MG

A synthetic GnRH peptide agonist that binds to GnRHR (Ki 0 3 nM in CHO cells expressing the human receptor) inhibits the growth of DU145 LNCaP and PC3 prostate and OVCAR-3 ovarian cancer cells (IC50s 62 1 73 4 98 1 and 67 7 M respectively) inhibits the growth of the TNBC HCC1806 and MDA-MB-231 cancer cell lines (EC50s 58 29 and 31 59 M respectively) stimulates FSH and LH release from primary rat pituitary cells at 50 nM decreases tumor volume of Dunning R3327H prostate tumor flank implants and reduces prostate and testis weight in rats at 1 mg/kg per day
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