Sigma Aldrich Fine Chemicals Biosciences DHP HM resin 100 200 mesh

Supplier:  Sigma Aldrich Fine Chemicals Biosciences 8550790005

A highly versatile support for the solid phase immobilization of primary secondary alcohols [1-11] phenols [12] purines [13] and indoles [14]. Derivatization is effected by treating the support in DCM with an excess of alcohol in the presence of a catalytic amount of pyridinium p-toluenesulfonate. A similar DHP-based support has also been used for the immobilization of tetrazoles [15].Release of the product alcohol from the support has been carried out by treating with 95% TfA/5% water [1] and TfA/DCM/EtOH [2 12]. However the use of TfA can lead in some cases to trifluoroacetate formation. Methods which eliminate this potential side reaction include PPTS/BuOH/DCE [3] TosOH in DCM [16] and TosOH in DCE/BuOH [17]. The product number for this product was previously 01-64-0192.To obtain a certificate of analysis (CoA) of a lot that begins with the letter A please select the option in the right hand menu Request a COA for Lots starting with A.

Catalog No. 50-290-1048