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Medchemexpress LLC DI-1859 | 2247061-09-0 | 99.6% | C30H45N5O3S | 1 ML
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Supplier:  Medchemexpress LLC HY14573310MM/1ML

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DI-1859 is a potent, selective, and covalent inhibitor of DCN1. It inhibits neddylation of cullin 3 in cells at low nanomolar concentrations. DI-1859 increases NRF2 protein, a CRL3 substrate, in mouse liver and protects mice from acetaminophen-induced liver damage.

  • Potent, selective, and covalent inhibitor of DCN1
  • Inhibits neddylation of cullin 3 in cells
  • Increases NRF2 protein in mouse liver
  • Protects mice from acetaminophen-induced liver damage
  • For research use only

Catalog No. 50-003-55924


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