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Medchemexpress LLC DI-82 | 1638148-50-1 | >98.0% | 510.65 | 25 MG
Supplier: Medchemexpress LLC 25MGHY136499
DI-82 is a potent deoxycytidine kinase (dCK) inhibitor with an IC50app of 27.8 nM and Kiapp of 9.2 nM. It exhibits antitumor activity, making it suitable for various research applications in oncology and cell biology.
- Potent deoxycytidine kinase (dCK) inhibitor
- Exhibits antitumor activity
- IC50 of 3.7 nM in CCRF-CEM acute lymphoblastic leukemia cells
- NADPH-dependent CLint of 22.7 μL/min·mg and T1/2 of 102 minutes in microsomal liver clearance assay
- Completely blunts the ability of decitabine to bind human thymidylate synthase (TS)
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