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Medchemexpress LLC di-Pal-MTO | 1349197-90-5 | 98.4% | 917.27 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1487025MG

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di-Pal-MTO is a palm oil-based lipid created by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When formulated into nanoparticles with mono-Pal-MTO in a 1:1 molar ratio, it demonstrates effective siRNA cell delivery and enhanced anticancer activity. This combination has been shown to significantly reduce tumor cell viability by 81% and tumor size by 83% in vitro, outperforming Lipofectamine 2000-mediated transfection.

  • Palm oil-based lipid, combining mitoxantrone (MTO) and palmitoleic acid.
  • Effective siRNA cell delivery, enhanced anticancer activity.
  • Forms nanoparticles (1:1 molar ratio with mono-Pal-MTO) for effective siRNA delivery.
  • Enhances in vitro antitumor activity, reducing tumor cell viability by 81% and tumor size by 83%.

Catalog No. 50-003-62084


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