Di-tert-butyl dicarbonate, 97+%

Description

CAS: 24424-99-5 | C10H18O5 | 218.249 g/mol

Reagent for the introduction of the Boc protecting group.Di-tert-butyl dicarbonate is a reagent used for the introduction of BOC protecting group. It plays an important role in the preparation of 6-acetyl-1,2,3,4-tetrahydropyridine by reacting with 2-piperidone. It serves as a protecting group used in solid phase peptide synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Reagent for the introduction of the Boc protecting group.Di-tert-butyl dicarbonate is a reagent used for the introduction of BOC protecting group. It plays an important role in the preparation of 6-acetyl-1,2,3,4-tetrahydropyridine by reacting with 2-piperidone. It serves as a protecting group used in solid phase peptide synthesis.

Solubility
Miscible with decalin, toluene, carbon tetrachloride, tetrahydrofuran, dioxane, alcohols, acetone, acetonitrile and dimethylformamide. Immiscible with water.

Notes
Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Moisture and light sensitive. Incompatible with oxidizing agents, reducing agents, bases and acids.

Specifications

Chemical Identifiers

• CAS: 24424-99-5
• Molecular Formula: C10H18O5
• Molecular Weight (g/mol): 218.249
• MDL Number: MFCD00008805
• InChI Key: DYHSDKLCOJIUFX-UHFFFAOYSA-N
• Synonym: di-tert-butyl dicarbonate, boc anhydride, boc-anhydride, di-t-butyl dicarbonate, di-tert-butyl pyrocarbonate, bis tert-butoxycarbonyl oxide, di-tert-butyldicarbonate, boc2o, di-t-butyl pyrocarbonate, di tert-butyl carbonate
• PubChem CID: 90495
• ChEBI: CHEBI:48500
• IUPAC Name: tert-butyl (2-methylpropan-2-yl)oxycarbonyl carbonate
• SMILES: CC(C)(C)OC(=O)OC(=O)OC(C)(C)C

• Melting Point: 21°C to 24°C
• Density: 0.95
• Boiling Point: 56°C to 57°C (0.5 mmHg)
• Flash Point: 37°C (99°F)
• Odor: Mild
• Assay Percent Range: ≥97%
• Refractive Index: 1.409
• Quantity: 25 g
• UN Number: UN2930
• Beilstein: 1911173
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with decalin,toluene,carbon tetrachloride,tetrahydrofuran,dioxane,alcohols,acetone,acetonitrile and dimethylformamide. Immiscible with water.
• Formula Weight: 218.25
• Percent Purity: ≥97%
• Chemical Name or Material: Di-tert-butyl dicarbonate

Safety and Handling

Hazard Category	H228-H315-H317-H318-H330-H335-H500
Hazard Statement	GHS H Statement H330-H318-H228-H315-H317-H335 Fatal if inhaled. Causes serious eye damage. Flammable solid. Causes skin irritation. May cause an allergic skin reaction. May cause respiratory irritation.
Precautionary Statement	P210-P240-P241-P260-P264b-P271-P272-P280-P284-P302+P352-P304+P340-P305+P351+P338-P310-P312-P333+P313-P362-P370+P378q-P501c
DOTInformation	Hazard Class: 6.1; Packaging Group: II
EINECSNumber	246-240-1
RTECSNumber	HT0230000
TSCA	Yes
storageNote1	Moisture sensitive
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only