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Medchemexpress LLC Dianhydrodulcitol; Dianhydrogalactitol | 23261-20-3 | 98.0% | 146.14 | 1 ML
SDP

Catalog No. 5000391842
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VAL-083 is an alkylating agent designed for research use, primarily known for creating N7 methylation on DNA and exhibiting antitumor activity. It suppresses cancer cell growth, induces apoptosis, and inhibits the proliferation of various cancer cell lines in a dose-dependent manner.

  • Alkylating agent that creates N7 methylation on DNA.
  • Suppresses U251 and SF188 cell growth and induces apoptosis.
  • Inhibits the proliferation of various cancer cell lines in a dose-dependent manner.
  • Suppresses migration and invasion by reducing MMP2, VEGF, VEGFR2, and FGF2 expression.
  • Induces cell cycle arrest at G2/M phase in glioma cell lines.
  • Enhances radiosensitivity and inhibits angiogenesis.
  • Blocks growth of LN229 cells in mice, with an 83.58% tumor growth inhibitory rate.
  • Potential multitarget agent for glioblastoma; new treatment option.

Catalog No. 50-003-91842 Supplier Medchemexpress LLC Supplier No. HY1651310MM/1ML
May include imposed supplier surcharges.
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VAL-083 is an alkylating agent designed for research use, primarily known for creating N7 methylation on DNA and exhibiting antitumor activity. It suppresses cancer cell growth, induces apoptosis, and inhibits the proliferation of various cancer cell lines in a dose-dependent manner.

  • Alkylating agent that creates N7 methylation on DNA.
  • Suppresses U251 and SF188 cell growth and induces apoptosis.
  • Inhibits the proliferation of various cancer cell lines in a dose-dependent manner.
  • Suppresses migration and invasion by reducing MMP2, VEGF, VEGFR2, and FGF2 expression.
  • Induces cell cycle arrest at G2/M phase in glioma cell lines.
  • Enhances radiosensitivity and inhibits angiogenesis.
  • Blocks growth of LN229 cells in mice, with an 83.58% tumor growth inhibitory rate.
  • Potential multitarget agent for glioblastoma; new treatment option.

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