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Medchemexpress LLC Dibenzothiophene | 132-65-0 | MFCD00004969 | 99.9% | 25 G
Supplier: Medchemexpress LLC 25GHYB0973
Dibenzothiophene is an orally active and noncompetitive CYP1A inhibitor, primarily used for studying developmental toxicity mechanisms. It inhibits CYP1A-mediated EROD activity with a Km of 0.592 μM and interacts with the AHR pathway. This compound enhances the embryotoxicity of β-naphthoflavone and shows acute toxicity in mice.
- Orally active and noncompetitive CYP1A inhibitor
- Inhibits CYP1A-mediated EROD activity
- Interacts with the AHR pathway
- Enhances embryotoxicity of β-naphthoflavone
- Used for studying mechanisms of developmental toxicity
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