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Medchemexpress LLC Dibutyryl-cGMP sodium | 51116-00-8 | 99.7% | 100 MG
Supplier: Medchemexpress LLC HY130354100MG
Dibutyryl-cGMP sodium is a cell-permeable cGMP analogue. It preferentially activates cGMP-dependent protein kinase (PKG), inhibits the release of [3H]-arachidonic acid from γ thrombin-stimulated human platelets, and induces peripheral antinociception through ATP-sensitive K+ channel activation.
- Cell-permeable cGMP analogue
- Preferentially activates cGMP-dependent protein kinase (PKG)
- Inhibits release of [3H]-arachidonic acid from γ thrombin-stimulated human platelets
- Induces peripheral antinociception via activation of ATP-sensitive K+ channels
- Induces process elongation and branching in astrocytes
- Prevents stress fibre formation and induces stellate morphology in cerebellar astrocytes
- Prevents RhoA-membrane association
- Accelerates wound closure in scratchwound model
- Antagonizes the hyperalgesic effect of PGE2
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