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Cayman Chemical DIclofenac amIde 1g
Supplier: Cayman Chemical 219691 G
A prodrug form of diclofenac; decreases paw thickness in a rat model of carrageenan-induced paw edema at 100 μmol/kg; decreases acetic acid-induced writhing in mice at 100 μmol/kg; has reduced ulcerogenicity in rats compared to diclofenac; a degradation product of diclofenac resulting from photo-transformation or spontaneous cyclization in strongly acidic pH conditions; has been used as a synthetic intermediate in the synthesis of compounds with anticancer activity as well as compounds with COX-1, COX-2, and/or 5-LO inhibitory activity
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