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Medchemexpress LLC Diclofenac (diethylamine) | 78213-16-8 | C18H22Cl2N2O2 | 5 G
Supplier: Medchemexpress LLC HY15036A5G
Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent that acts as a COX inhibitor. It has IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Additionally, it induces apoptosis of neural stem cells (NSCs) by activating the caspase cascade.
- Potent and nonselective anti-inflammatory agent: acts as a COX inhibitor.
- Target specificities: IC50s of 4 nM for human COX-1 and 1.3 nM for human COX-2 in CHO cells.
- Ovine COX inhibition: IC50s of 5.1 μM for ovine COX-1 and 0.84 μM for ovine COX-2.
- Apoptosis induction: induces apoptosis of neural stem cells (NSCs) via activation of the caspase cascade.
- Available in 5 G variant.
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