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Medchemexpress LLC Diclofensine hydrochloride | 34041-84-4 | 99.8% | 358.69 | 5 MG

Supplier: Medchemexpress LLC HY186105MG
Diclofensine (hydrochloride), also known as Ro 8-4650 hydrochloride, is an orally active neuronal monoamine uptake inhibitor. It effectively blocks the reuptake of dopamine, noradrenaline, and serotonin in rat brain synaptosomes, with IC50 values of 0.74, 2.3, and 3.7 nM, respectively. This compound has been shown to potentiate norepinephrine-induced hypertension while attenuating Tyramine-induced hypertension. It is recognized for producing psychostimulant and mood-elevating effects without the common issues of sudden disappearance or withdrawal reactions, making it a valuable tool in the research of moderate to severe depression.
- Blocks the uptake of dopamine, noradrenaline, and serotonin
- Potentiates norepinephrine-induced hypertension
- Attenuates Tyramine-induced hypertension
- Produces psychostimulant and mood-elevating effects
- Used in the research of moderate to severe depression
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