Diethyl dicarbonate, 97%

Description

CAS: 1609-47-8 | C6H10O5 | 162.14 g/mol

Ribonuclease inhibitorDiethyl dicarbonate acts as an inhibitor of ryanodine binding to ryanodine/calcium(II) receptor channel. It is useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Further, it inhibits platelet-activating factor acetyl hydrolase. In addition to this, it is involved in the modification reagent for His and Tyr residues in proteins.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ribonuclease inhibitorDiethyl dicarbonate acts as an inhibitor of ryanodine binding to ryanodine/calcium(II) receptor channel. It is useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Further, it inhibits platelet-activating factor acetyl hydrolase. In addition to this, it is involved in the modification reagent for His and Tyr residues in proteins.

Solubility
Miscible with chloroform, ethanol, esters, ketones and hydrocarbons. Slightly miscible with water.

Notes
Store in cool place. Incompatible with strong oxidizing agents, strong reducing agents, strong acids, strong bases and ammonia.

Specifications

Chemical Identifiers

• CAS: 1609-47-8
• Molecular Formula: C6H10O5
• Molecular Weight (g/mol): 162.14
• MDL Number: MFCD00009106
• InChI Key: FFYPMLJYZAEMQB-UHFFFAOYSA-N
• Synonym: diethyl pyrocarbonate, diethyl dicarbonate, depc, diethyl oxydiformate, baycovin, diethylpyrocarbonate, ethyl pyrocarbonate, dicarbonic acid, diethyl ester, dicarbonic acid diethyl ester, diethyl pyrocarbonic acid
• PubChem CID: 3051
• ChEBI: CHEBI:59051
• IUPAC Name: ethoxycarbonyl ethyl carbonate
• SMILES: CCOC(=O)OC(=O)OCC

• Density: 1.101
• Boiling Point: 93°C to 94°C (18 mmHg)
• Flash Point: 69°C (156°F)
• Assay Percent Range: 0.97
• Refractive Index: 1.398
• Quantity: 5 g
• Beilstein: 637031
• Sensitivity: Moisture sensitive
• Merck Index: 14,7998
• Solubility Information: Miscible with chloroform,ethanol,esters,ketones and hydrocarbons. Slightly miscible with water.
• Formula Weight: 162.14
• Percent Purity: 97%
• Physical Form: Liquid
• Chemical Name or Material: Diethyl dicarbonate

Safety and Handling

Hazard Category	H227-H302-H315-H319-H332-H335
Hazard Statement	GHS H Statement H302-H315-H319-H335-H227 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.
Precautionary Statement	P210-P235-P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P370+P378q-P501c
EINECSNumber	216-542-8
RTECSNumber	LQ9350000
TSCA	Yes
storageNote1	Moisture Sensitive
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only