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Apexbio Technology LLC Diethylmaleate 141-05-9 100mg
Supplier: Apexbio Technology LLC B6151100
Diethylmaleate (141-05-9) is a small-molecule compound that depletes intracellular glutathione (GSH) modulating cellular redox-sensitive pathways Diethylmaleate exerts its biological activity primarily through induction of oxidative stress and ROS generation leading to modulation of cell cycle apoptosis gene expression and activation of MAPK signaling pathways In vitro studies demonstrate that Diethylmaleate-mediated GSH depletion triggers cell cycle arrest and apoptosis Animal research shows effects on reproductive systems including altered testicular antioxidant status and sperm parameters Based on these pharmacological properties Diethylmaleate holds research potential in studies of oxidative stress redox regulation and toxicology
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