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Medchemexpress LLC Difopein TFA | 96.30% | 6387.17 (free acid) | 5 MG
Supplier: Medchemexpress LLC HYP1380A5MG
Difopein TFA is a specific and competitive inhibitor of the 14-3-3 protein, a highly conserved eukaryotic regulatory molecule. It functions by blocking the ability of 14-3-3 to bind to target proteins and inhibits 14-3-3/Ligand interactions. This compound is not cell permeable and induces apoptosis, enhancing the ability of Cisplatin to kill cells.
- Specific and competitive inhibitor of 14-3-3 protein
- Blocks 14-3-3 from binding to target proteins
- Inhibits 14-3-3/ligand interactions
- Induces apoptosis
- Enhances cisplatin's ability to kill cells
- Target: 14-3-3 protein
- Soluble in DMSO at ≥ 100 mg/mL
- In vivo soluble at ≥ 2.5 mg/mL with specific protocol
- Recommended storage for powder: -80°C for 2 years; -20°C for 1 year
- Recommended storage in solvent: -80°C for 6 months; -20°C for 1 month
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