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Medchemexpress LLC Dihydroergocristine mesylate | 24730-10-7 | 1 ML
Supplier: Medchemexpress LLC HYN231910MM/1ML
Dihydroergocristine mesylate (DHEC mesylate) is an inhibitor of γ-secretase (GSI) that effectively reduces the production of amyloid-β peptides associated with Alzheimer's disease. It directly binds to γ-secretase and Nicastrin, exhibiting high affinity. This product is for research use only.
- Inhibits γ-secretase activity in T100 cells without affecting cell viability
- Decreases cellular Aβ production
- Causes dose-dependent accumulation of carboxy-terminal fragments of APP (APP-CTFs)
- Reduces γ-secretase activity in fibroblast cells
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