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Medchemexpress LLC Dihydroergotamine mesylate | 6190-39-2 | 99.94% | 50 MG
Supplier: Medchemexpress LLC HYB0670A50MG
Dihydroergotamine mesylate is a BBB-permeable ergot alkaloid for the research of migraines. It reduces cell survival in A549 and NCI-H226 cells and inhibits cell survival in Hep3B, PLC/PRF/5, Huh7, and HepG2 cells.
- Reduces cell survival in A549 and NCI-H226 cells
- Inhibits cell survival in Hep3B, PLC/PRF/5, Huh7, and HepG2 cells
- Induces mitochondrial morphologic alterations and dysfunction
- Increases ROS generation and induces apoptosis
- Disturbs ATP production in A549 cells
- Inhibits STAT3 activation and enhances protein stability of Mcl-1
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