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Cayman Chemical DIhydroergotamInmesylate 50mg
Supplier: Cayman Chemical 2384750 MG
An agonist of 5-HT1B and 5-HT1D receptors (Kis = 0.3 and 2.5 nM, respectively, for human receptors); binds to dopamine D2 and D3 as well as 5-HT2A receptors (K0.5s = 5, 16, and 38 nM, respectively) but has lower affinity for D1, 5-HT2C, and 5-HT3 receptors (K0.5s = 2,779, 298, and >10,000 nM, respectively); binds to α-adrenergic receptors; increases the mechanical pain threshold in a rat model of neuropathic pain when used at doses of 50 and 100 mg/kg
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