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AdipoGen Dihydromyricetin (25 mg)
Supplier: AdipoGen CDXD0381M025
Chemical. CAS: 27200-12-0. Formula: C15H12O8. MW: 320.25. Dihydromyricetin is a flavanonol originally isolated from A. grossedentata. Dihydromyricetin has been demonstrated to show antioxidative, anti-inflammatory, anticancer, antimicrobial, cell death-mediating, neuroprotective and lipid and glucose metabolism-regulatory activities. It also has been found to have anti-alcohol intoxication effects, associated with its action as a positive modulator of GABA-A receptors at the benzodiazepine site. Dihydromyricetin may scavenge ROS to protect against oxidative stress or potentiate ROS generation to counteract cancer cells selectively without any effects on normal cells. Dihydromyricetin may be associated with several different molecules involved in cellular apoptosis, oxidative stress and inflammation, such as AMPK, MAPK, Akt, NF-kappaB, nuclear factor E2-related factor 2 (Nrf2), ATP-binding cassette transporter A1 (ABCA1) or peroxisome proliferator-activated receptor-gamma (PPARgamma).
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