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Cayman Chemical DIlInoelaIdIn 50mg
SDP

Supplier:  Cayman Chemical 2698050 MG

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A peptide hormone that lowers blood calcium level and inhibits bone resorption binds to hCTR2 with IC50 values of 0 933 0 224 0 134 and 0 317 nM alone and with RAMP1 2 or 3 respectively induces cAMP accumulation in COS-7 cells transfected with CTR2 (EC50 0 166 nM) inhibits bone resorption by osteoclasts in a pit formation assay using rat bone slices (ID50 0 003 pg/mL) and lowers calcium level in vivo in a bioassay of hypocalcemia in rats (ED15 33 9 mg/kg)

Catalog No. 50-294-0240


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