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Medchemexpress LLC Dimethyl fumarate | 624-49-7 | 100.0% | 144.13 | 1 ML
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Supplier:  Medchemexpress LLC HY1736310MM/1ML

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Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator that induces upregulation of antioxidant gene expression. It also induces necroptosis in colon cancer cells via the GSH depletion/ROS increase/MAPKs activation pathway, and promotes cell autophagy. Dimethyl fumarate is used for multiple sclerosis research.

  • Orally active and brain-penetrant Nrf2 activator
  • Induces upregulation of antioxidant gene expression
  • Induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway
  • Promotes cell autophagy
  • Used for multiple sclerosis research

Catalog No. 50-003-85992


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