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Medchemexpress LLC Dimethyl fumarate | 624-49-7 | 99.9% | 144.13 | 100 MG
SDP

Catalog No. 5000385525
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Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator that upregulates antioxidant gene expression. It induces necroptosis in colon cancer cells and can be used for multiple sclerosis research.

  • Reduces the viability of SGC-7901, HT29, HCT116, and CT26 cancer cells.
  • Activates JNK, p38, and ERK in CT26 cells.
  • Induces necroptosis in colon cancer cells via GSH depletion/ROS increase/MAPKs activation.
  • Inhibits dendritic cell (DC) maturation by reducing inflammatory cytokine production.
  • Suppresses HIV replication and neurotoxin release.
  • Attenuates 6-OHDA induced striatal oxidative stress and inflammation.

Catalog No. 50-003-85525 Supplier Medchemexpress LLC Supplier No. HY17363R100MG
May include imposed supplier surcharges.
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Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator that upregulates antioxidant gene expression. It induces necroptosis in colon cancer cells and can be used for multiple sclerosis research.

  • Reduces the viability of SGC-7901, HT29, HCT116, and CT26 cancer cells.
  • Activates JNK, p38, and ERK in CT26 cells.
  • Induces necroptosis in colon cancer cells via GSH depletion/ROS increase/MAPKs activation.
  • Inhibits dendritic cell (DC) maturation by reducing inflammatory cytokine production.
  • Suppresses HIV replication and neurotoxin release.
  • Attenuates 6-OHDA induced striatal oxidative stress and inflammation.

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