Dimethyl phthalate (DMP) is a plasticizer that imparts flexibility to rigid polyvinyl chloride (PVC) resin. It is also an orally active endocrine disruptor that can cause ovarian dysfunction in mice and induce oxidative stress and apoptosis in cells, impacting blood and red blood cell function in rats.
- Utilized as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin
- Functions as an oral active endocrine disruptor, potentially causing ovarian dysfunction
- Induces oxidative stress and apoptosis in cells
- Affects blood and red blood cell function in rats
- Promotes oxidative stress and apoptosis in SH-SY5Y cells in vitro
- Causes membrane damage in Escherichia coli K12 cells, increasing permeability and inducing oxidative stress
- Significantly impacts ovarian function by decreasing follicle-stimulating hormone (FSH) and increasing estradiol (E2) and luteinizing hormone (LH)