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Selleck Chemical LLC Dinaciclib S2768-200mg
Supplier: Selleck Chemical LLC S2768200MG
Dinaciclib is a novel and potent CDK inhibitor for CDK2 CDK5 CDK1 and CDK9 with IC50 of 1 nM 1 nM 3 nM and 4 nM in cell-free assays respectively It also blocks thymidine (dThd) DNA incorporation Dinaciclib induces apoptosis through the activation of caspases 8 and 9 Phase 3
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