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AdipoGen Dioscin (25 mg)
Supplier: AdipoGen CDXD0195M025
Chemical. CAS: 19057-60-4. Formula: C45H72O16. MW: 869.04. Dioscin is a natural steroid saponin originally isolated from plants used in herbal remedies. It has anticancer, anti-inflammatory, immunoregulatory, antioxidant, hyoplipidemic, antiviral, neuroprotective and antifungal activities. It inhibits proliferation, induces autophagy and oxygen-mediated apoptosis in cancer cells. It has been shown to inhibit colon tumor growth and tumor angiogenesis through regulating VEGFR2 and AKT/MAPK pathways. It inhibits adipogenesis through the AMPK/MAPK pathway. Dioscin showed protective effect against liver fibrosis by potently inhibiting ITGA5. Promotes proliferation of pancreatic beta cells via Wnt/beta-catenin signaling pathways. It has been shown inhibit the nuclear transport of NF-kappa and the expression of reactive oxygen species (ROS) and consequently the expression of inflammasome targets such as NLRP3.
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