Diphenhydramine hydrochloride, 99%, Thermo Scientific Chemicals

Description

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
A histamine H1 receptor antagonistDiphenhydramine hydrochloride acts as a sodium channel blocker. It is used as a histamine H1-receptor antagonist. Further, it is used as a sedative, hypnotic, antiemetic, antitussive and pruritus. It is employed in the treatment of allergic conditions. In addition to this, it is used as an active ingredient in common cold preparations.

Solubility
Soluble in water, dimethyl sulfoxide, dimethylformamide, methanol and ethanol.

Notes
Incompatible with strong oxidizing agents, strong acids and alkalis.

Specifications

Chemical Identifiers

• CAS: 147-24-0
• Molecular Formula: C17H22ClNO
• Molecular Weight (g/mol): 291.82
• MDL Number: MFCD00012479
• InChI Key: PCHPORCSPXIHLZ-UHFFFAOYSA-N
• Synonym: diphenhydramine hydrochloride, dimedrol, diphenhydramine hcl, carphenamine, bendylate, carphenex, cathejell, denydryl, diphamine, eldadryl
• PubChem CID: 8980
• ChEBI: CHEBI:4637
• IUPAC Name: hydrogen [2-(diphenylmethoxy)ethyl]dimethylamine chloride
• SMILES: [H+].[Cl-].CN(C)CCOC(C1=CC=CC=C1)C1=CC=CC=C1

• Melting Point: 168°C to 169°C
• Quantity: 50 g
• UN Number: UN2811
• Sensitivity: Light sensitive
• Solubility Information: Soluble in water,dimethyl sulfoxide,dimethylformamide,methanol and ethanol.
• Formula Weight: 291.82
• Percent Purity: 99%
• Chemical Name or Material: Diphenhydramine hydrochloride

Safety and Handling

Hazard Category	H302
Hazard Statement	GHS H Statement H351-H361-H302-H315-H319-H335 Suspected of causing cancer. Suspected of damaging fertility or the unborn child. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	205-687-2
RTECSNumber	KR7000000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only