Diphenylphosphonic azide, 97%

Description

Store cold | CAS: 26386-88-9 | C12H10N3O3P | 275.20 g/mol

Diphenylphosphonic azide acts as a reagent for the synthesis of peptides and phosphoramidates by reacting with amines. It is also used in the preparation of oligosaccharides linked with carbamate and urea bonds utilizing modified Curtis rearrangement. It is involved in pseudohalogen replacement of the azido group by treatment with nucleophilic reagents, such as water, butanol, ammonia, and various amines. Further, it is used as a hydroazidation catalyst for preparation of organoazides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Diphenylphosphonic azide acts as a reagent for the synthesis of peptides and phosphoramidates by reacting with amines. It is also used in the preparation of oligosaccharides linked with carbamate and urea bonds utilizing modified Curtis rearrangement. It is involved in pseudohalogen replacement of the azido group by treatment with nucleophilic reagents, such as water, butanol, ammonia, and various amines. Further, it is used as a hydroazidation catalyst for preparation of organoazides.

Solubility
Immiscible with water.

Notes
Store in a cool place. Incompatible with acids and oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 26386-88-9
• Molecular Formula: C12H10N3O3P
• Molecular Weight (g/mol): 275.20
• MDL Number: MFCD00001987
• InChI Key: SORGEQQSQGNZFI-UHFFFAOYSA-N
• Synonym: diphenylphosphoryl azide, diphenyl azidophosphate, diphenylphosphonic azide, diphenyl phosphoryl azide, diphenyl phosphorazidate, phosphorazidic acid, diphenyl ester, azido phenoxy phosphoryl oxy benzene, dppa polymer-bound, diphenylphosphorazidate, unii-gxm91165av
• PubChem CID: 123414
• IUPAC Name: [azido(phenoxy)phosphoryl]oxybenzene
• SMILES: [N-]=[N+]=NP(=O)(OC1=CC=CC=C1)OC1=CC=CC=C1

• Density: 1.275
• Boiling Point: 161°C to 162°C (0.5 mmHg)
• Flash Point: >110°C (230°F)
• Assay Percent Range: 97%
• Refractive Index: 1.552
• Quantity: 5 g
• UN Number: UN3278
• Beilstein: 2058967
• Solubility Information: Immiscible with water.
• Formula Weight: 275.2
• Percent Purity: 97%
• Physical Form: Liquid
• Chemical Name or Material: Diphenylphosphonic azide

Safety and Handling

Hazard Category	H301-H310+H330-H315-H319-H335
Hazard Statement	GHS H Statement H301-H311-H331-H315-H319-H335 Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P260-P262-P264b-P270-P271-P280-P284-P301+P310-P302+P350-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P361-P363-P501c
DOTInformation	Hazard Class: 6.1; Packaging Group: II
EINECSNumber	247-644-0
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only