Cayman Chemical DIpIvefrInhydrochlorIde 100mg

Supplier:  Cayman Chemical 24028100 MG

A GAD inhibitor reduces GAD activity by 60 when administered at a dose of 39.8 mol/g per hour ex vivo in mouse brain preparations i.p. administration (1.2 mmol/kg) induces convulsions and decreases GABA concentration throughout the cerebellum pons medulla striatum cortex and hippocampus in mice chronic administration (3.2 g/0.5 l per hour for 13 days) increases locomotor activity in an open field test and impairs attention in the 5-choice serial reaction time task (5CSRTT) inhibits GAD in vitro only when used at high concentrations (1-80 mM)

Catalog No. 50-293-2564